
A fully open-lid centrifuge is a separation machine used to separate mixtures of solids and liquids (liquid and liquid), yielding separate solids and liquids (or liquid and liquid). The centrifuge works by recombining mixtures of different densities. Solids typically settle to the bottom, while a clear liquid forms on top. This stratification depends on the acceleration due to gravity. To meet the needs of industrial production, the centrifuge was developed to separate liquid mixtures more quickly and efficiently.
Fully Open-Lid Centrifuge
Fully open-lid centrifuges rotate at high speeds, generating powerful centrifugal force. Their centrifugal separation coefficient is typically hundreds, thousands, or even tens of thousands of times greater than the acceleration due to gravity, resulting in very fast separation speeds. However, due to the significant differences in the properties of different materials, centrifuges of various specifications have been developed. Centrifuges for general solid-liquid separation typically operate at speeds below 3000 rpm. Mixtures with finer particles and smaller density differences require centrifuge speeds of 8000 to 30000 rpm for separation.
The main principle of a fully open-top centrifuge is to utilize the centrifugal force generated by a high-speed rotating centrifugal drum (equipped with appropriate filter material) to accelerate the liquid phase of the solid-liquid mixture out of the drum, while retaining the solid phase inside, achieving solid-liquid separation, or dehydration.
When a suspension containing fine particles is stationary, the suspended particles gradually sink due to gravity. The heavier the particle, the faster it sinks, while particles with a density less than the liquid will float. The velocity of particles in a gravitational field depends on the particle's size, shape, and density, as well as the strength of the gravitational field and the viscosity of the liquid. Under normal gravity, particles the size of red blood cells, with diameters of a few micrometers, can be observed.
The main principle of a sedimentation centrifuge with a fully open lid is to utilize the powerful centrifugal force generated by the high-speed rotation of the rotor to accelerate the sedimentation rate of components (solid or liquid) with different proportions in a mixed liquid, separating substances with different sedimentation coefficients and buoyant densities.
Additionally, when substances settle in a medium, diffusion occurs simultaneously. Diffusion is unconditional and inversely proportional to the mass of the diffusing substance; the smaller the particle, the more severe the diffusion. Sedimentation, on the other hand, is relative and conditional, requiring external force to propel it. It is directly proportional to the weight of the settling object; the larger the particle, the faster the sedimentation. For particles smaller than a few micrometers, such as viruses or proteins, which exist in a colloidal or semi-colloidal state in solution, the sedimentation process cannot be observed by gravity alone. Because smaller particles settle more slowly and diffuse more severely, a fully open lid centrifuge is needed to generate a powerful centrifugal force, forcing these particles to overcome diffusion and settle.